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Monday, April 18, 2011 hassan ahmed, Community Member, asks

Q: What is the relationship between triptans and heart diseases?

Iam on zolmitriptan,I take 2-3 tablets(2.5mg) during my migraine attack.The medication seems to improve the situation which sometimes lasts for several days.Iam 62 years old.A doctor advised me  to stop taking triptans since they are not recommended for those over 50,because of their adverse effect on the heart.

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Answers (1)
Teri Robert, Health Guide
4/20/11 3:50pm



The prescribing information for the triptans says that triptans shouldn't be used by patients with a history of or risk factors for coronary artery disease. The Zomig information suggests it not be used by males over 40 "UNLESS a cardiovascular evaluation provides satisfactory clinical evidence that the patient is reasonably free of coronary artery and ischemic myocaridal disease or other significant underlying cardiovascular disease."


There is no evidence that triptans have any adverse effects on a healthy heart. The concern is that an older heart may not be healthy.


Some doctors continue to prescribe triptans for patients well beyond this age as long as they've had cardiovascular evaluations that show no problems.



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By hassan ahmed, Community Member— Last Modified: 04/24/11, First Published: 04/18/11