So, what is a doctor to do about the abuse of pain-killers? If doctors begin to act like police officers, then the doctor-patient relationship suffers. But doctors can keep an eye out for certain risk factors which may indicate a current or future problem with narcotics in a given patient. A recent article in the "Annals of Internal Medicine" discusses such risk factors, which include mood disorders, other addictions, younger age, and male sex. Unfortunately, there are few novel treatments for pain, and therefore doctor and patient are often left only with narcotics, which have been around for a long, long time. It would be helpful to have other weapons in the fight against chronic or recurrent pain, weapons which are less addictive. In the meantime, industry and the medical profession are looking at ways to combat abuse of prescription pain-killers. For example, Oxycodone will soon be available embedded in a viscous gel. In this form, the pill cann...
Researchers have discovered why many fibromyalgia patients complain that even strong narcotic pain medications fail to relieve their pain. A study at the University of Michigan Health System found that the mu-opioid receptors (MOR) in people with fibromyalgia had a reduced ability to bind to the drugs targeting them. The researchers did positron emission tomography (PET) scans of 17 women who had fibromyalgia and 17 women who did not. Results showed that the fibromyalgia patients had reduced MOR availability within regions of the brain that normally process and dampen pain signals –– specifically, the nucleus accumbens, the anterior cingulate and the amygdala. Opioid medications work by binding to opioid receptors in the brain and spinal cord. When those receptors have a lowered availability, the painkillers may not be able to bind to the receptors as well as they should, which means they cannot alleviate pain as effectively. Among the drugs that would be affected b...
I took a oxycodone 5mg and 15 min later was given a toradol shot. Is this safe? Amy.
There are no significant interactions between these two medications to make the combination unsafe.
That said, it doesn't mean they're safe for you. It depends on more than those two medications. It also depends on all other medications you're taking and any medical issues you may have. Hopefully, you remembered to tell the doctor who ordered the Toradol about the oxycodone, and he or she considered that before ordering the Toradol.
Good luck, John Claude Krusz and Teri Robert
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