Hello, mariposa,
The is a tough situation. With hemiplegic Migraine, it is strongly advised that hormonal birth control be avoided because of the risk of stroke associated with both Migraine and hormonal birth control.
That said, during a pregnancy, there are many "normal" warnings that can go out the window to protect the pregnancy. This is one of them. Prometrium is commonly used to avoid miscarriage.
Sadly, this may be a case when the benefits of the prometrium for the pregnancy are weighed against the risks to the mother, your daughter, and that makes a situation that's beyond difficult.
Am I understanding correctly that the same doctor is treating her Migraines and managing her pregnancy? What kind of doctor is she?
It's really impossible for us to make any suggeestions about taking or not taking the Prometrium. That type of suggestion can really only be made by a doctor who is caring for your daughter.
BUT, sitting here thinking about what I'd do if she were my daughter, I think some second opinions are in order. I would want those second opinions to be from a Migraine specialist and an expert OB/GYN, who give their opinions after consulting with each other.
It's important to note that neurologists aren't necessarily Migraine and headache specialists. Take a look at the article Migraine and Headache Specialists - What's So Special? If you need help finding a Migraine specialist, check our listing of Patient Recommended Migraine and Headache Specialists.
You and your daughter are bound to be going through a rough time. If you'd like some additional support, come join our discussion forum. You'll need to register again once there because it's a separate membership database, but you can use the same member name, email address, and password that you used here. You can find our forum at http://forums.healthcentral.com/discussion/migraine/forums.
Mariposa, please keep in touch and let us know how things are going? We do wonder how people are doing after we answer these questions.
Good luck,
Teri