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I am also trying to find a solution to my migraine pain and symptoms.  My symptoms have not paralyized me but I have had similiar symptoms.  I experience numbness in my arms, tongue, nose and fingers.  When I take migraine meds I don't experince the numbness.  I get very anxious with every migraine because I do get very disorenented and have problems with slurred speech.  I am 35 years old and I have a 1 year old and a 3 year old.  I was going to try a beta blocker to see if that would help me.  I hope your wife finds a solution.  I would rec. a decreasing caffine,sugar and alcohol intake.  I think that might be my problem too.