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I have had the migraine demon for 24 years. Chronic as a teen and again for the last ten years or so. I have been on Topamax for over 3 years. For the past 1 1/2 years I have been on 450mg of Topamax (225 twice a day). You do need to realize that as Topamax goes up memory loss can happen. Simple things, like the spelling of words, words don't come to your mind easily or people names. Your doctor can decide to increase your meds but only you can decide if memory loss is worth it. For me it was.-Jenifer

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