Hi Michelle,

Nortriptyline, aka Pamelor, is a tricyclic antidepressant and is sometimes used to treat Migraine disease.

A few things to keep in mind when starting a new drug - it may take up to three months to adjust to it and see a reduction in Migraine frequency. Side effects are potential which means they don't happen to everyone all the time.

If you find this medication is not reducing your pain, don't lose hope. There are over 100 medicationa available for Migraine prevention.  Migraine Preventive Medications - Too Many Options To Give Up!

Good luck.

Nancy Bonk

Hi Michelle I was takeing up  to 100mg of Nortriptyline a day my side effects were, very dry mouth could not hardly taste the food I ate, tired feelings all day. I have since stopped taken them all together. Because of the side effects.   I can say that it did reduce the intensity and frequency of my migraines. Hope you dont have the same side effects that I had.

I've taken nortriptyline & toprol for migraine for >10 yrs.  I gradually worked up from 30 to 50 & then in recent years, increased to 150 mg for chronic pain mgmt as well.  When I first started taking it, I felt like a zombie even at the introductory low dose.  Nortriptyline has less effect of weight gain that some of the other antidepressants.  I only gained a few lbs.  I did not have any other side effects, but every body is different.  I believe it has helped me.