You're welcome again, Jill!   The whole stroke issue would have your doctors looking at PFO closure under a different light.   And, stroke risk is certainly considered before prescribing triptans.   Midrin has been under a lot of discussion for quite some time. It's a great medication for lots of people. It was unavailable for a while because of a shortage. Now, it appears that the original Midrin may have been entirely discontinued by the manufacturer. I have a call in to them now to veryify. In any case, it's worth discussing with your doctor.   Please keep in touch and let me know you're doing? I so often wonder about peopole who have asked questions.   with a hug, Teri PS: Thanks for your comments on my book. I'm glad it's been a help to you!