No, Midrin isn't a triptan. There are seven medications in the triptan family-- Imitrex, Maxalt, Zomig, Amerge, Relpax, Axert, and Frova -- as well as Treximet, which is a combination of Imitrex and Naproxen Sodium. Triptans are selective serotonin receptor agonists. One way they work is by binding to different combinations of serotonin receptors.   Midrin is a compound medication containing acetaminophen, dichloralphenazone, and isometheptene mucate. As you know, acetaminophen is a simple analgesic, a simple pain reliever. Dichloralphenazone is a mild sedative that slows down the central nervous system. Isometheptene does have the action of reversing the dilation of blood vessels. For some reason, that's not seemed to be an issue with Midrin/Duradin. It may be that the action is less then or more gentle than with triptans. That's something you'll want to check with your doctor.   Hope that helps!Teri