http://news.sciencemag.org/sciencenow/2011/06/lsd-alleviates-suicide-headaches.html?ref=hp

                                                                                                            short link here:

http://alturl.com/daoay                                                                             

While the study was for cluster headaches, it may also work on migraines since there is a serotonin connection. LSD is mistaken for serotonin and it binds to most 5-HT receptors. This may be interesting to follow.                                                                                                      

Quote below . . .

                                                                                                               "There seems to be a long-term prophylactic effect that we cannot explain," Halpern says. The team has since treated a seventh patient with similar results. "Compared to what these headache sufferers currently have available to them, this is quite remarkable. It could lead to a near-cure-like treatment", Halpern says."