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Tuesday, March 30, 2010 EYE AND HEAD MIGRAIN, Community Member, asks

Q: APAP 325 / BUTALBITAL 50 /CAFF 40 MG what is Butalbital ? How does this combination work?

I have migrains, I was perscribed APAP 325/BUTALBITAL 50/ CAFF 40MG TAB.  I

get short term results, sometimes  I feel I need to repete the dose before I should.  What is BUTALBITAL? WHAT DRUG FAMILY DOES IT BELONG TO?

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Answers (1)
Nancy Harris Bonk, Community Member
3/31/10 5:03pm



Butalbital is a short/medium acting barbiturate potentially habitforming. This type of medication won't prevent a Migraine attack, instead is used as a rescue medication when triptans don't work or people are unable to use them. keeping track of the different kind of Migraine medications can be confusing at times, so when you get a chance take a look at  Preventive, Abortive, and Rescue Medications - What's the Difference?



How much of this medication are you using? Taking Migraine abortive meds such as the triptans or ergotamines or any kind of pain medication, like the one you mentioned more than two or three days a week can make matters worse by causing medication overuse headache (MOH), aka rebound. See Medication Overuse Headache - When the Remedy Backfires for more information on this.


In addition there is now evidence that ANY use of opioids or barbiturates increases the risk of transformed Migraine. You can find more information about this in Transformed Migraine - Risk Increased by Some Medications.



Good luck




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By EYE AND HEAD MIGRAIN, Community Member— Last Modified: 05/21/14, First Published: 03/30/10