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I can't say that I have ever split an Imitrex, as I usually need at least 100 mg to knock out a migraine.  For me, it takes about 30 minutes after taking a tablet for it to kick in.  I do not think the tablets are coated,  so I do not see why you couldn't split them.  You might also try the statdose injection.  The shot is self-administered and feels like a hefty bee-sting, but the migraine relief is more immediate.  I keep both as options and judge which to take when based on how fast the onset of the migraine is.  I have been battling the migraines for over 20 years...good luck getting rid of yours.