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-:¦:-•:*'""*:•.-:¦:-•*Welcome to MyMigraineConnection!*•-:¦:-•:*'""*:•.-:¦:- Thanks for being so thorough with your details. Wow. I feel for you. That's quite some list. We can't give medical advice, but let me see if I can think of any information to share with you. OK?   Have your Migraines gotten worse since your sleep pattern got messed up? Sleep issues can be a big trigger. Do you know what triggers all of your Migraines?   Is it safe to assume that when the side effects weren't dangerous, you tried the preventives for about three months each to give them time to "kick in?" As thorough as you are, I'd imagine the answer is, "Yes," but can't be certain without asking.   One thought on prevention -- depending on where your Migraines begin, there may be some nerve block options to be tried.   According to Migraine specialists and researchers, there's about 3% of Migraineurs for whom they can't find effective preventive regimens. A good Migraine specialist won't give up finding that regimen and may suggest trying things that aren't on our list. He or she will understand that you want your life back and will look for a way to give you relief as many days as possible without risking putting you into an MOH cycle. If any of the abortives work for you, they may say to take that abortive a couple of days a week and give you a pain medication that you can use a couple of other days a week.   I really wish I had something more concrete to offer you. Please feel free to continue a conversation here if you'd like.   If you'd like some additional support, come join our discussion forum. You'll need to register again once there because it's a separate membership database, but you can use the same member name, email address, and password that you used here. You can find our forum at http://forums.healthcentral.com/discussion/migraine/forums.   with a gentle hug, Teri