I'm not quite sure what you're asking here. Topamax and Maxalt are quite frequently taken at the same time with the Topamax being taken daily for Migraine prevention and Maxalt taken to abort a Migraine when it occurs.
But, to answer the question about how long Topamax is in your system - the half-life of Topamax is 21 hours, so 97% of it would be out of your body after 105 hours.
If there's any question about how you should be taking these medications, please call your doctor's office.
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