Hi tamms4,

There are plenty of other options other than Topamax if you feel it isn't working for you. May I ask how long you have been taking it? Sometimes it can take our bodies up to three months to adjust to new medication before we see a reduction in the frequency and severity of our Migraines. We have information on Topamax you can see HERE.

Now having said that, there are over 100 medications that can be used for Migraine and headache prevention that it's literally impossible to have your doctor suggest there is nothing left to try. You can find a list of potential Migraine and headache preventives in Migraine preventive medications - too many options to give up! 

I know you're going through a rough time. If you'd like some additional support, come join our discussion forum. You'll need to register again once there because it's a separate membership database, but you can use the same member name, email address, and password that you used here. You can find our forum at http://forums.healthcentral.com/discussion/migraine/forums.

 If your doctor isn't able to help you, it may well be time to consult a Migraine and headache specialist. It's important to note that neurologists aren't necessarily Migraine and headache specialists. Take a look at the article Migraine and Headache Specialists - What's So Special? If you need help finding a Migraine   specialist, check our listing of Patient Recommended Migraine and Headache Specialists.

A few other things if I may. We can unwittingly create another problem if we are taking Migraine abortive meds such as triptans or any kind of pain med more than two days a week, a big part of your problem may well be medication overuse headache (MOH), aka rebound. See Medication Overuse Headache - When the Remedy Backfires for more information on this. If you're in an MOH situation, nothing you take is going work, neither prescription nor "natural" medications nor over-the-counter. If that's the case, you need to work with your doctor to stop the medications causing the problem. 

ANY use of opioids or barbiturates and frequent use of triptans and NSIADs are associated with increased risk of transformed Migraine. See Transformed Migraine - Risk Increased by Some Medications for more information on this.

I hope this helps.

Nancy