Is this about migraines? Because I feel the same way. I was put on a low dose of wellbutrin 75 mg because I am depressed and also just made an apt. to see a pyschiatrist who specializes in patients who have chronic pain. We need to admit when it is too much. It is helpful for me to hear someone else feeling the same way. I also made lots of other specialist appointments, like phyical therapy and massage therapy. I have been making an effort work out more, actually I call them "work throughs" because I can't work out for fear of getting a migraine. It's hard, and isolating. I couldn't take my daughter to swim class today and spent the day in bed. This is my first year as a mother, I should be enjoying this not spending it in bed. However, use your support systems and try to put yourself first. I too and tired of drugs and find that they are no longer working for me. I just posted about switiching from generic to regular to see if it could make a different but don't want to get my hopes up. Good luck and I'm here if you want to talk more!

Thanks for bringing this up, Eshuler. I have just come out of a sever (#7-8) 65 hour migraine where the meds I have had only minor effect and I spent most of those hours in pain, with little sleep, just trying to get through it, and finally last night, the pain started to break, and although the migraine is still there, it is around the 3-4 level now, and going down to a 2 level which I can work with and live with since I have that most every day.  I too fell like I am out of options with medications, since the ones I have - 1 triptan which I cannot take much of or too often, and 1 med that has some opiate in it knocks me out so badly I don't like to take it.  My system has gotten so sensitive that I am not the same as I was when I was 40 and I could take any amount of medication and tolerate it.  

As Teri said there are so many new medications out now, go to a neurologist who specializes in headaches.  The difference between regular neurologists and specialists is so great that you will be amazed at the support they will be able to give you. I get depressed mostly from frustration at not being able to do things I want to do, and being stopped by these horrible headaches.  Just know that we all get frustrated by this, and you have a lot of company, but the migraines end, and there is a lot of help out there to get the migraines managed and help you have a productive life and keep them under control.

So stay in touch, there is a lot of information on this site.  Look at the all the topics, read them, find a good specialists and make an appointment, keep a diary of what you are eating, and everything else that is suggested on this site, and educate yourself.  If you have done all that already, you are one step ahead.  Just write everything down, and work with your doc, or drs. and revise your tx. plans to make your life workabe.  We are all rooting for you here!