Don't recall weight issues, however, I got a kidney stone from Topamax.  I am doing so poorly again and had no success with so many drugs that my doctor is talking about trying the topamax again.  This time he would work with a urologist to change the pH of my urine to (hopefully) prevent kidney stones.  I am scared to death by this but don't know what else to do.  I am not sure I can walk around worrying about another kidney stone and I am not sure if I can go on like this with migraines all the time.  Now possibly from meds + an antibiotic that put me over the edge I am having severe stomach problems too.  So many complicated health issues that is ruining my life and that of my family.  It is so hard.  And that people don't understand.  I've been in the hospital because I can't let the migraines go due to previous stroke and increased risk of stroke with prolonged migraine.  And, while there have had nurses make reference to "drug seekers".  Now am also schedule for second occiptal nerve block as first did not work.  I don't know what to do anymore.