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Monday, November 23, 2009
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Winter Holiday GuideEnjoying the Holidays Despite Migraines and Headaches --> Info for you...

Migranal Nasl

Drug Interactions


Generic Name: DIHYDROERGOTAMINE - NASAL
Pronounced: (dye-HI-dro-er-GOT-uh-meen)

Migranal Nasl Interactions

See also Warning section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur:

  • azole antifungals (e.g., ketoconazole, itraconazole, posaconazole)
  • macrolide antibiotics (e.g., clarithromycin, erythromycin, troleandomycin, telithromycin)
  • protease inhibitors (e.g., ritonavir, nelfinavir, indinavir, amprenavir)
  • non-nucleoside reverse transcriptase inhibitors (e.g., delavirdine, efavirenz)


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting dihydroergotamine.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • vasoconstrictors (e.g., epinephrine, dopamine)
  • beta blockers (e.g., propranolol)
  • nicotine (e.g., cigarettes, nicotine gum/patches)
  • nitrates (e.g., isosorbide, nitroglycerin)
  • a certain type of antidepressant (SSRIs such as fluoxetine, paroxetine, sertraline)


If you are currently using a 5-HT1 agonist (e.g., sumatriptan, methysergide), avoid taking it for 24 hours before and after taking dihydroergotamine. Consult your doctor or pharmacist for more details and for advice on how to time your doses of these medications.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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