Sign in

or Register now

MyMigraineConnection.com

See all of our health sites at www.HealthCentral.com
Wednesday, October 8, 2008

Depakote Oral

Drug Interactions


Generic Name: DIVALPROEX SODIUM ENTERIC-COATED TABLET - ORAL
Pronounced: (dye-VAL-pro-ex SO-dee-um)

Depakote Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • certain antidepressants (e.g., amitriptyline, nortriptyline, phenelzine)
  • certain benzodiazepines (e.g., clonazepam, diazepam)
  • doripenem
  • mefloquine
  • other medications for seizure (e.g., carbamazepine, ethosuximide, felbamate, lamotrigine, phenobarbital, phenytoin, topiramate)
  • rifampin
  • warfarin
  • vorinostat
  • zidovudine


Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually these dosages are 81-325 milligram per day), should be continued. Consult your doctor or pharmacist if you are using aspirin for any reason.

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as:

  • antihistamines that cause drowsiness (e.g., diphenhydramine)
  • medicine for sleep (e.g., sedatives)
  • muscle relaxants
  • narcotic pain relievers (e.g., codeine)
  • psychiatric medicines (e.g., phenothiazines such as chlorpromazine)
  • tranquilizers


Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about the safe use of those products.

This drug may affect certain lab tests (e.g., urine ketones). Make sure laboratory personnel and your doctors know you use this medication.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

Ask a Question

Get answers from our experts and community members.

Answer a Question

useing a anticonvulsant as a preventative only to have it cause you siezures

Answer This View all questions >
Free Newsletter
Get weekly updates, news alerts and more on Migraine and related health conditions.