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Does Depakote Decrease Serotonin?
Hyperserotonemia; Serotonergic syndrome
Treatment
Patients with serotonin syndrome should stay in the hospital for at least 24 hours for close observation.
Treatment may include:
- Benzodiazepines such as diazepam (Valium) or lorazepam (Ativan) to decrease agitation, seizure-like movements, and muscle stiffness
- Cyproheptadine (Periactin), a drug that blocks serotonin production
- Fluids by IV
- Withdrawal of medicines that caused the syndrome
In life-threatening cases, medicines that keep...
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