Medications To Prevent Migraines

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Medications for Preventing Migraine Attacks

The Food and Drug Administration has approved five drugs for prevention of migraine:

  • Propanolol (Inderal)
  • Timolol (Blacadrene)
  • Divalproex sodium (Depakote)
  • Topiramate (Topamax)
  • OnabotulinumtoxinA (Botox)

Propanolol and timolol are beta-blocker drugs. Divalproex and topiramate are anti-seizure drugs. Many other drugs are also being used or investigated for preventing migraines.


Beta-blockers are usually prescribed to reduce high blood pressure....

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