In October of 2010, Botox (onabotulinumtoxinA) was approved by the FDA for the treatment of chronic Migraine. This prompted many discussions of its use for Migraine prevention. Among those discussions, I remember at least one in which some people decided they would not use Botox because it was tested on lab animals.
Allergan, the manufacturer of Botox, recently announced FDA approval of a new analysis method that replaces animal testing. To share this good news with you, here's the press...

