Topamax And Pregnancy

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FDA Alert: Topamax Taken During Early Pregnancy Increases Risk of Cleft Defects

The FDA has issued a new warning about the use of Topamax (topiramate) during pregnancy.  Topamax is an anticonvulsant medication also approved for Migraine prevention.  Like other anticonvulsants, Topamax is sometimes used off-label for chronic pain – particularly neuropathic or nerve pain. 

New information from the North American Antiepileptic Drug (AED) Pregnancy Registry shows an increased risk of oral clefts (cleft lip and cleft palate) in infants exposed to topiramate during the...

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