Migraine Preventive Medications - Too Many Options To Give Up!

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Attention Deficit Hyperactivity Disorder Meds
Selective Norepinephrine Reuptake Inhibitor:

amphetamine/dextroamphetamine, aka Adderall
atomoxetine HCl, aka Strattera
methylphenidate, aka Concerta

ARTHRITIS MEDS
Cox-2 Enzyme Inhibitors:

celecoxib, aka Celebrex

NEURONAL STABILIZING AGENTS (antiseizure meds)

carbamazepine, aka Tegretol
clonazepam, Klonopin
clorazepate, aka Tranxene
divalproex, aka Depakote
gabapentin, aka Neurontin
levetiracetam, Keppra
lamotrigine, aka Lamictal
pregabalin, aka Lyrica
oxcarbazepine, Trileptal
tiagabine, aka Gabitril
topiramate, aka Topamax
valproate Sodium, aka Depacon
zonisamide, aka Zonegran

Ergot Alkaloid:

methylergonovine, aka Methergine (the only ergot used as a preventive)

Leukotriene Blockers:

montelukast, aka Singulair
zafirlukast, aka Accolate
zyleuton, aka Zyflo

Atypical Antipsychotic Medications:

olanzapine, aka Zyprexa
quetiapine, aka Seroquel
ziprasidone, aka Geodon

Other:

baclofen, aka Lioresal
botulinum Toxin Type A, aka Botox

Dietary Supplements:

coenzyme Q10
feverfew (Should not be used by women who are or could become pregnant.)
butterbur, aka Petadolex
magnesium
vitamin B2
5-HTP (Check carefully with doctor because of interactions with meds including triptans)
lecithin
melatonin

Appliances:
If a temperomandibular joint disorder (TMJ), bruxism (grinding your teeth), or clenching your jaw are Migraine triggers for you, you may want to check into the NTI Tension Suppression System (NTI-TSS). This is a small dental appliance worn at night to keep the molars and canines from touching. It was developed by Dr. Jim Boyd, and has been helpful for people with these triggers. (See www.nti-tss.com.)

This list will be updated as more treatments are successfully used for headache and Migraine prevention. If you're having problems finding an effective preventive regimen, sharing this list with your doctor may be helpful to you.

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References:

Ramadan, Nahib M., MD; Silberstein, Stephen D., Md, FACP; Frietag, Frederick G., DO; Gilbert, Thomas T., MD, MPH; Frishberg, Benjamin M., MD. "Evidence-Based Guidelines for Migraine Headache in the Primary Care Setting: Pharmacological Management for Prevention of Migraine." American Academy of Neurology Practice Guidelines. September, 2000.