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Have You Tried Low-Dose Naltrexone?
There seems to be a subculture of patients who have tried low-dose naltrexone (LDN) to treat a variety of conditions from autoimmune diseases such as multiple sclerosis, to Alzheimer’s disease, to HIV/AIDS and cancer. Does it work? Fans of the treatment say yes; but it’s practically impossible to know because few double-blind clinical trials have taken place. How many people have tried LDN, for what disease, and with what outcomes? We don’t know because these patients are rarely tracked, and some may not even tell their doctors they have used this drug off-label. What is low-dose naltrexone (LDN)? Naltrexone is a drug approved by the FDA for the treatment of opioid addiction. Opioids are medications that relieve pain. The typical dosage of naltrexone for opioid addiction is 50mg to 100mg daily. LDN refers to daily dosages of naltrexone that are in the range of 3mg to 4.5mg. At this level, naltrexone has analgesic and anti-inflammatory properties not seen with larger doses and “may represent one of the first glial cell modulators to be used for the management of chronic pain disorders” (Younger, 2014). Have studies explored LDN therapy and MS? In three sm
Have You Signed Up to Receive the MS HealthCentral Newsletter?
HealthCentral has launched the new MS Newsletter. It's easy to subscribe here. For those who did not see our first monthly newsletter this past Friday, I’m posting the contents below. You can also subscribe to my own posts here. Living with Multiple SclerosisWelcome to our new Multiple Sclerosis newsletter! I'm excited to bring you stories, news, and information designed to educate, empower, and inspire our community. You are receiving this email because you have subscribed to the MS newsletter through HealthCentral or one of our sister sites. As a subscriber, you will enjoy exclusive content about MS, general health, and living well despite adversity. Click here if you'd like to edit your HealthCentral newsletter preferences. Live well and be bold my friends,Lisa Emrich @lisaemrichMS Expert and Community Leader, HealthCentral
âBut You Donât Look Sickâ
Have you ever heard the often dreaded remark,”But you don’t LOOK sick!”? Knowing how to respond can be tough. But if you are feeling anything less than your personal best, the saying just might unleash your hidden dragon. Watch out - that angry dragon is difficult to harness once let loose. It only takes spending a little time in the world of invisible illness to develop a sensitivity to the perceptions of others. So many misunderstandings abound in our world. At times, living with a chronic disease, especially one that commonly has few outward signs, creates a cognitive dissonance between how you feel inside and what you want others to see. What are visible signs of dysfunction? A cane or wheelchair becomes an outward symbol that you may have difficulty walking. People who see you using a mobility device may or may not realize that you need extra considerations and offer to be helpful when you encounter difficulties. Try not to hold it against them. A cast worn on a broken limb is an easily accepted outward indication that you have suffered an injury. Others may not know how you broke your bone, but they probably realize that you are not functioning at 100% level. It may be more likely that someone would offer to do things for you because they understand that you are
Living a Fulfilling Life with MS
Here's my story of my first symptoms of MS, my early "non-diagnosis," and how my world has changed.
New Meta-Study Confirms MS Increases Fracture Risk
Studies have found that the overall bone mineral density (BMD) is much lower in MS patients compared to healthy individuals, leading to an increased risk of osteoporosis and reduced bone mass. Several symptoms of MS—muscle weakness, poorer postural balance, stiffness, numbness, tingling, impaired vision, fatigue, dizziness, disability, or spasticity—may contribute to falls in people living with MS. It follows logically that with the incidence of weaker bones and increased risk of falls, people with MS may also be at increased risk of bone fractures. Reduced bone density and history of fracture in MS A study among 9,346 MS patients registered with NARCOMS found that 27.2% of participants surveyed reported low bone mass, while more than 15% of responders reported a history of fracture after the age of 13 years. A small study of 40 men with MS (mean age: 51.29 ± 8.7 years) found that 80% of participants, tested by DEXA scan, had reduced bone mass of either the lumber spine or the femoral neck. Of these, 17 patients (42.5%) had osteopenia and 15 patients (37.5%) had osteoporosis. Eight patients (21%) had previously experienced bone fractures in the extremities
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