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Untitled Comment
Paul
Thursday, September 25, 2008 at 11:48 AMre: Untitled Comment
Merely Me
Thursday, September 25, 2008 at 06:05 PMIt is true...every drug has side effects. I did worry a bit but I was not taking a super high dose and I wasn't on it for very long. There are a lot of people who are doing clinical trials of the newest MS drugs to stop the progression of this disease. I can't imagine...not knowing if you were even taking the real thing or not. I am very appreciative of those people.
Thank you so much for your comment and keep coming to read and share!
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Food for Thought
Mandy Crest
Thursday, September 25, 2008 at 02:09 PMI have no experience with oral prednisone, so I really appreciate all the information you've provided here. Food for thought, should the need ever arise.
re: re: Food for Thought
Mandy Crest
Thursday, September 25, 2008 at 06:50 PMI've done the drip twice, and what an experience THAT is! Whew! I was manic for about 7 days -- couldn't sleep, couldn't stay still, and couldn't shut up for more than 30 seconds at a time! The MS symptoms faded and I gained unbelievable strength and stamina.
The downside of that is obvious, plus at the end of a week, I crashed BIG time, and I do mean BIG!
I've decided that, taking into account all the risks, I will not do the drip again unless I have brand new symptoms, especially where eyesight is concerned. I believe that we always need to keep our options open.
Anyway, that's my history of the Solu-Medrol drip.
re: re: re: Food for Thought
Lisa Emrich
Friday, September 26, 2008 at 01:46 PMMandy,
You didn't do an oral steroid taper after the drip?
That sounds harsh to me, however I do believe that Prednisone is one of the most evil drugs I've taken. He and I don't agree eye-to-eye on a few things. Decadron is much friendlier to this ol' gal.
Wow, I guess I'm the steroid master of the group (sarcasm dripping). My credentials -
1. Oral prednisone at 1000mg/day (3 days) followed by 14 day taper.

2. IV Solumedrol drip at 1g (5 days) followed by 14 day prednisone taper.
3. IV Solumedrol drip at 1g (5 days) followed by 14 day decadron taper.
4. Medrol DosePak taper starting at 12mg.
5. IV Solumedrol drip at 1g (5 days) followed by 14 day decadron taper.
6. Oral prednisone taper starting at 60mg.
Experience #1 was in 2000. Experiences #2-6 have been during past three years.
Do I win a prize??
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Untitled Comment
Anonymous
Thursday, September 25, 2008 at 04:20 PMI always like to know of a real person's experience with any drug I have to take, perhaps because it seems the labels all are scary these days. I know we are all different and reactions and effects will vary, but I do find these types of articles helpful. Thanks for this information.
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Untitled Comment
rwboughton
Thursday, September 25, 2008 at 11:52 PMI have not personally taken prednisone, but I am familiar with its effects from when I used to operate an adult foster care with my now ex-wife. Not that prednisone had anything to do with the dissolution of the marriage. One of the ladies had to take prednisone (I forget exactly why), and what I remember is that it made her very hungry and it caused her to be rather whacky. She would insist, for instance, that there was a cow in the backyard trying to get into her room. It seems like one of those things where she had trouble with it, and trouble without it. I guess that's what getting old is all about.
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Oral solumedrol
Julie
Friday, September 26, 2008 at 01:48 PMI've taken prednisone a couple of times and think it was helpful. I experienced the insomnia but really didn't notice much of a difference otherwise. I've done the solumedrol drip once and it left me so shaky (tho i was already very shaky) and I wasn't sure if my slow recovery from that episode was due to the steriod or just normal circumstances.
Recently, my dr. told me I needed another round of solumedrol drip and I declined, partly because of the arm port they kept in me for several days. It was very uncomfortable and I didn't need any more pain added. My dr let me try oral solumedrol, which she warned would taste like battery acid and would be very harsh on my stomach. I agreed to do it and was very pleasantly surprised at how easy that went and the huge price difference too. The pharmacy was taken aback at the order but they helped me mix it (takes a syringe but really isn't difficult). I was careful about sipping it over a period of an hour to ease it into my system and eating a full meal to protect my stomach. I mixed it with cranberry juice and really didn't have a problem with the taste.
I think my copay on oral solumedrol was $20 vs. hundreds of dollars for the drip. While the drip is technically supposed to go directly into the bloodstream and be a superior way to go, I was quite happy to go this route and will be my steroid method of choice if/when I need to do this again.
I've found that for me the steroid benefit isn't immediate. I feel worse and then slowly get better over a couple of weeks.
re: Oral solumedrol
Merely Me
Saturday, September 27, 2008 at 08:57 AMThis is really excellent information...just the sort of thing I want to know. I already have tummy troubles so I wonder how that would go for me. I suppose everyone has a different reaction to these drugs. I am a lot more prepared now hearing of your personal experience. Thank you so much for sharing your story here.
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My dance with the drugs...
Kathy Flores
Friday, September 26, 2008 at 10:51 PMHi Merely Me,
In October 07 I first tried the Oral prednisone taper and it didn't do much for my symptoms so shortly afterward as my symptoms got worse, I went in for the IV Solumedrol drip at 1000 mg/day (3 days). That was harsh. During those 3 days my food tasted like crap (copper actually), I slept little but I sure did get A LOT of stuff around the house done. I have never done the drug crack but at times I felt like I was tweaking out like someone on crack. I'm sure I was pretty difficult to live with at that time. However, the drip helped the symptoms release.
I probably should have gone in for the drip during my last relapse in Feb 08 and think that on the last couple of days when I was deciding to go in, it started to let up.
Given the choice, if I were headed into another bad relapse, I'd have no problem getting back on that IV.
My sister has gone on the IV drip many times and now wonders if it's less effective because she's done it so often. I don't know the answer but she says her doctor warned her not to overdo it. Anybody have the experience that the IV drip started to become less effective after many uses?
Kathy
re: My dance with the drugs...
Merely Me
Saturday, September 27, 2008 at 09:12 AMDon't quote me on this but yes I was reading somewhere that docs don't like to do the drip too much because of the very reason you are saying...that sometimes it loses its effectiveness. Not sure what constitutes "too much" though.
I am so glad you are sharing your experience as I have yet to use Solu-Medrol and now I know what I can potentially expect.
This is the kind of information you just cannot get from anywhere else but from hearing of another's personal experience. I really appreciate your comment.
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prednisone
aisha m
Friday, October 03, 2008 at 06:16 PMI was often given prednisone when I was younger for my asthma and that was never an issue. I gained weight and felt jittery but usually whatever symptom I had was so much better that I didn't mind the side effects from the prednisone.
But recently I was given solumedril drip and a prednisone taper for an MS flareup and solumedril was crazy! I couldn't eat anything without upsetting my stomach. I could barely sleep and I was wired with so much energy that I scared my husband. It gave me a bad case of acne and I never had bad skin, even in high school.
Thankfully the prednisone taper helped since I had no crash but a month after the drip I am still tired since I had no time to really rest since I have been working the entire time. I don't ever want to take solumedril again but it was interesting to have an extra 5 hours a day and a ton of energy to get a ton of stuff done.
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Experienced the exact same positive symptons on Prednisone
Anonymous
Wednesday, May 06, 2009 at 12:25 AMI fell into an exacuberation the exactly two years to the date of my original dx. I had never tried the drug, but it has served me well. I started out with the 6,5,4,3,2,1 over 21 days. I am now on 40mg a day and still trying to figure out the pattern to avoid the hormonly change. So I take it late at night and wake at 5:30a ready to go just like before. Around 4pm, I am tired need to rest I also have to sometimes take a valium to get to sleep. But the pain leaves my body completely.
Thank you so much for sharing your story.
Jennifer Cardenas
re: Experienced the exact same positive symptons on Prednisone
Spam33
Sunday, October 18, 2009 at 01:44 PMI am 27 now and have been diagnosed with MS since I was 18, after my diagnosis I had my first prednisome bout I had oral prednisone for about a wekk and the side effects were really not noticeable, after that I have had not only oral prednisone but other oral steroids and I had the solumedrol drip for about a week and a half which had to be done at the hospital since I had never had it before and I also had it once after that as an outpatient treatment. The weight gain is nothing compared to the symptons you also get this high energy right after but then crash once you are off, always make sure they taper you off slowly because is not a drug that you can just stop taking, I wish everyone on here the best of luck with whatever medical battle yu are fighting and I thank all those who serve in the clinical trials for new medicines, always remember that no matter what a positive attitude in any adverse situation will help not only you and your loved ones but everyone around.
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Thank you so much for your comment!







Since you, according to your profile take no drugs, your MS episodes must have been very worrisome and frightening to seek medication to begin with. I'm happy to hear prednisone helped with minimal side-effects.
It's sobering to begin a drug with so many possibly harmful effects, as most do have; it's easy think they always happen to someone else. Only having a friend with MS, I can say it worked for them too. During that time, the amount of activity was astounding, it was amazing to see what something was causing right before you, it was amazing. The MS episodes, the new ones, subsided.
Such balances a chronic condition bring. Choosing between the help and harm of drugs. Imagine what people went through who voulnteered to do the humna trials of these drugs!