steroids for relapses

What Is It Like to Take Oral Prednisone?

Merely Me Health Guide September 25, 2008
  • I was recently prescribed oral Prednisone to deal with an MS exacerbation and I wanted to tell you all about my experience.    What is Prednisone?   Prednisone is  part of a class of drugs called corticosteroids which also includes Methylprednisolone, and dexamethaso...

35 Comments
  • Merely Me
    Health Guide
    Jan. 03, 2012

    Hello

     

    I haven't commented here in some time but seeing all the new comments prompted me to talk about my latest time with prednisone.

     

    It worked great.  I didn't have the jitters I normally would get.  I also didn't take as much as a previous time. When I was taking it I felt like I could walk through fire.  I had energy.  My...

    RHMLucky777

    Read More

    Hello

     

    I haven't commented here in some time but seeing all the new comments prompted me to talk about my latest time with prednisone.

     

    It worked great.  I didn't have the jitters I normally would get.  I also didn't take as much as a previous time. When I was taking it I felt like I could walk through fire.  I had energy.  My MS symptoms stopped.  I felt great.

     

    That is...until I stopped it.

     

    The last time I took prednisone the after effects were not so good.  Let's talk yeast.  I had oral thrush.  I had never had it before and it was horrific.  My tongue, palate, mouth was burning for like over a week.  I had to get another medication to deal with that.  My body felt like I had been run over by a train.  I also caught a virus right after stopping it.  This had never happened before so I don't know what happened.

     

    I felt like I was being punished for how well it had worked. 

     

    Hopefully I won't have to take it again for a long time.  I feel a little cautious about it now but...it sure did take away my MS symptoms.

     

    Thanks to everyone who has responded to this post. 

     

    MM

    • Cathy
      Health Guide
      Jan. 03, 2012

      Merely Me,

       

      I think I was meant to see your original posting from '08 on steroids.  As you know, I've had MS for 25 years.  I've taken prednisone many times (I have RRMS and been on Copaxone 15 yrs).  Steroids are not working for me this time - in fact I am getting worse.  I started out last week with 10 pills/10 mg for 2 days, then...

      RHMLucky777

      Read More

      Merely Me,

       

      I think I was meant to see your original posting from '08 on steroids.  As you know, I've had MS for 25 years.  I've taken prednisone many times (I have RRMS and been on Copaxone 15 yrs).  Steroids are not working for me this time - in fact I am getting worse.  I started out last week with 10 pills/10 mg for 2 days, then 9, and so forth.  Today I took my 3 pills. I started out with my legs getting more numb before the prednisone - now my entire body is numb (including head, lips..), and I am weak.  This has never happened to me before.  I will be calling the doctor tomorrow.  Not a lotta fun, eh?

    • Merely Me
      Health Guide
      Jan. 03, 2012

      I am so sorry Cathy.

       

      It is something how each time on prednisone can be like a brand new experience.  You will have to report back on what your doctor says and what you can use instead of the prednisone.  Maybe it just isn't strong enough for this flare.  Have you ever had the solu-medrol drip?

       

      Hope you feel better soon.  Let...

      RHMLucky777

      Read More

      I am so sorry Cathy.

       

      It is something how each time on prednisone can be like a brand new experience.  You will have to report back on what your doctor says and what you can use instead of the prednisone.  Maybe it just isn't strong enough for this flare.  Have you ever had the solu-medrol drip?

       

      Hope you feel better soon.  Let us know what happens. 

    • Cathy
      Health Guide
      Jan. 03, 2012

      I've had the solumedrol but, however idiotic, my insurance company would not approve the IV, thus the orals.  I will let you know tomorrow what the doctor says.  Thanks for getting back to me so quickly - you are always right there.

       

      Have a wonderful evening,

      Cathy

    • Merely Me
      Health Guide
      Jan. 10, 2012

      Just checking back to see how you are doing Cathy.

       

      I think I am having a flare at present and am going to see my neurologist tomorrow.  I see Prednisone in my future. 

       

      Hope you are doing okay.

       

      MM

  • garden lady
    Aug. 24, 2012

    Severe swelling and intense pain in my right thumb sent me to the doctor for relief. I am 65 and an avid gardner with joint pain in my hands for the past year, but I could tolerate it with 1 Aleve in a.m. and p.m. prior to this latest 2 day marathon of pruning and weeding in my garden.

     I was prescribed a 6 day regimine of prednisone...

    RHMLucky777

    Read More

    Severe swelling and intense pain in my right thumb sent me to the doctor for relief. I am 65 and an avid gardner with joint pain in my hands for the past year, but I could tolerate it with 1 Aleve in a.m. and p.m. prior to this latest 2 day marathon of pruning and weeding in my garden.

     I was prescribed a 6 day regimine of prednisone with 4mg tablets.  1st day 2 bkfst, 1 lunch, 1 supper, 2 bed; 2nd day 1 bkfast, 1 lunch, 2 dinner, 1 bedtime; 3rd day 1 bkfst, 1 lunch, 1 dinner, 1 bed time and decreasing down to 1 tablet on the   6th day. 

    I am on the second day of the prednisone, 800 mg. of ibuprophen  1tab.4 times a day, and 500 mg of hydrocodone every 4 hours as needed.  The relief is amazing; within the first 8 hours of taking the meds, the intense swelling and throbbing/burning pains has diminished. I can now touch me thumb and index finger and middle finger.  I do use ice and a hand brace as part of the therapy.  I only need 1/2  tablet of hydorcodone every 6 hours.  At the end of this second day of prednisone, I became flushed in the face (like too much sun).  I have read that this is a common side effect of the medication.  I have not had difficulty sleeping.  My appetite is deminished and must force myself to eat with each dose of meds.   

  • Anonymous
    Barbie
    Jun. 19, 2012

    I have been on prednisone for a bladder disease since April.  Last week I was down to 1/2 pills (5 mg) and this week I stopped.  I am experiencing sweats, chills, pins and needles, numbness, back ache, skin hurts - is this normal??????

    • curious
      Sep. 03, 2012

       

       

      It's 2 am and I'm up searching for answers and am relieved to stumble upon this sharing of information about prednisone.   I see my curious side effects here, and can stop worrying so much!!!!  I was given 10 mg prednisone, 17 pills,  over one week for severe back pain. When I told people I was taking Prednisone, every reaction...

      RHMLucky777

      Read More

       

       

      It's 2 am and I'm up searching for answers and am relieved to stumble upon this sharing of information about prednisone.   I see my curious side effects here, and can stop worrying so much!!!!  I was given 10 mg prednisone, 17 pills,  over one week for severe back pain. When I told people I was taking Prednisone, every reaction was some form of "YUK"  I Didn't know what that meant exactly, but now I do!!!      The pain DID go away, BUT--the side effects are MISERABLE, STILL AFTER FIVE WEEKS and I don't think I would do this again.

           Here is what happened:    I was immediately hungry all the time and at the end of 7 days had gained 5 pounds, which is By far the least of my concerns.  I didn't feel off balance, but evidently was spacially challanged-- I fell 4 times within days, and regularly mis-judged space so that I bumped into doorframes, etc, resulting in numerous painful bruises on my arms and legs.    I immediately developed a yeast infection along with a thrush-like condition in my mouth.  Have tried numerous anti-yeast Drugs but after 5 weeks, the the itching and burning senstions over my body, along with chllls, and itching small pimple like blisters on my thighs--- continues.  Every day brings a new "issue"---and have been concerned about developing a staph infection, then today I have a sty in my eye!  I've gone from a formerly no drug person to a multi-drug person with cremes and pills they are prescribing for the symptoms--which for the most part are uneffected by the drugs!  Upon taking the pills, I immediately began to feel anxious and fearful with OVER THE TOP anxiety (reached it peak 3rd  week after stopping taking the drug, but has continued into the 5th week.)  For the last month have been unable to remember my work responsibilities from moment to moment, and during the nite continuous dreams with anxiety ---actually "working" all night long in my mind going over my work to do, but then during waking hours unable to think of the next thing I should be doing.   

             I went out of town the 4th week after stopping the drug,  and was fearful, anxious, disoriented, almost unable to function. Anxiously called my co-workers numerous times about various business concerns, lost my room key three times, lost track of time, could not remember what I was supposed to do the next moment. Called home anxously and regularly, and my husband said I "had to change my mindset or I WOULD have a heart attack"  but I couldn't stop stressing!  The worst part was I WATCHED myself doing all these things and feeling this way, but was unable to stop it or effect it!!!  

       

      Thank heavens I found this web-page and now I know I'm not going crazy, as I'm reading all of my sypmptoms in these posts!!!  THANK YOU ALL for sharing!!!  

         

    • Mina001
      Sep. 03, 2012

      Hi Curious,

       

      Well, you sound like you have had a ride with Prednisone.  Even on a semi low dose of 10mg, you seem to have little tolerance for the drug.  I feel for you and have had many of the symptoms that you seem to be having but I am still on the drug at 15mg daily.  I have been on Prednisone for almost 6 months with doses as high...

      RHMLucky777

      Read More

      Hi Curious,

       

      Well, you sound like you have had a ride with Prednisone.  Even on a semi low dose of 10mg, you seem to have little tolerance for the drug.  I feel for you and have had many of the symptoms that you seem to be having but I am still on the drug at 15mg daily.  I have been on Prednisone for almost 6 months with doses as high as 60 mg and the side effects were horrible.  They still continue at 15 mg but not as severe but I have no choice but to be on it right now. 

      I want you to know that Prednisone is scary drug at least in my mind and it did not help me with my blood platelets as it was supposed to do. 

      I have not been able to be totally off the drug so I cannot speak for the weaning off process and how long it actually takes to get out of your system.  I have not personally heard too many accounts of 10mg causing that severe of problems but having said that each person is different and side effect severity would be different as well.

      One thing I have learned is to find a doctor that listens to your concerns and does not dismiss any symptom however weird or insignificant they may think it is because it is real to you.  I really hate the speech problems and loss of concentration and thought process.  It really does raise havoc with your life but I am glad that you are off of the drug and Good Luck with getting back to normal.

       

      Mina

    • Post prednisone
      Jan. 12, 2013
      I am wondering if you are feeling better as I had the same experiences.
    • Post prednisone
      Jan. 12, 2013
      I am wondering if you are feeling better as I had the same experiences.
  • Mina001
    Feb. 03, 2012

    New Lupus diagnosis with low platelet count.  Being put on prednisone 40 mg a day for a 4 week regiment. I have chronic pain and inflamation but it is the platelet count that is suppose to rebound on prednisone.  I don't want to take it but it seems to be a silent killer just like high blood pressure.  I want to raise my platelet count on my...

    RHMLucky777

    Read More

    New Lupus diagnosis with low platelet count.  Being put on prednisone 40 mg a day for a 4 week regiment. I have chronic pain and inflamation but it is the platelet count that is suppose to rebound on prednisone.  I don't want to take it but it seems to be a silent killer just like high blood pressure.  I want to raise my platelet count on my own but so far no response to the foods suggested.  I have watched my daughter have significant weight gain and jitterness from this medication. I am very leary but don't know what else to do at this point.  I would suffer through the pain without it if the platelets were not involved.  So, I am supposed to start today, thinking of just taking 20 mg and see what the platelets do.  The lower the dose the better to me.  All of your comments were very helpful to read but I am still scared.

    • Cathy
      Health Guide
      Feb. 03, 2012

      Mina,

       

      Don't be as afraid as you are - my wish for you!  In my opinion, you should start taking the Prednisone as your doctor directed and see how you do.  Take something like Zantac for your stomach, and watch what you eat.  I just did a 2 wk dose of orals and didn't gain a pound.  I gain very easily, but not this time.  I drank...

      RHMLucky777

      Read More

      Mina,

       

      Don't be as afraid as you are - my wish for you!  In my opinion, you should start taking the Prednisone as your doctor directed and see how you do.  Take something like Zantac for your stomach, and watch what you eat.  I just did a 2 wk dose of orals and didn't gain a pound.  I gain very easily, but not this time.  I drank at least 64 oz of water a day, and ate as lightly as I could.  While you are taking your dosage, if you have any issues you could always call your doc and have him taper you off more quickly.  Although your daughter is your blood relative, it doesn't necessarily mean you will react to the steroids in the same manner.  Hope this helps.....

    • Mina001
      Feb. 03, 2012

      Thanks, I think that the whole idea of having a chronic condition with various and sundry side conditions is a bit over whelming at present.  I know I shouldn't compare others as we are all different I just don't like new medications.  I have been on a low dose of blood pressure medicine for years and have no problems and just don't like to add anything...

      RHMLucky777

      Read More

      Thanks, I think that the whole idea of having a chronic condition with various and sundry side conditions is a bit over whelming at present.  I know I shouldn't compare others as we are all different I just don't like new medications.  I have been on a low dose of blood pressure medicine for years and have no problems and just don't like to add anything new but my body says otherwise.  I am looking into alternative diets and therapies to hopefully boost my platelets but I don't know. This is all so new. I am a hard person to get to take anything.  I had a hysterectomy and would not take anything because the pain killer gave me one episode of that out of body experience and that was it.  I have two prespcriptions for pain sitting on my bedside that I have not even cracked open because I just fight through it.  Stubborn I guess because I hate funky feelings.  I will try it but probably only the 20 mg and see how I do first.  I all ready have problems sleeping even with the fatigue, I really don't need any jittery feelings.  Anyway, sorry to go on, I thank you for your response.

  • Anonymous
    Allen
    Jan. 03, 2012

    What does the medication do to assist in pulminary problems.

     

    E' menges5@knology.net

     

    1SG USA, Ret (78YO)  Info will not be used in any way to circumvent the Doctor.

    A. M.

  • akakroke
    Oct. 23, 2011

    The article and comment thread was so good that I felt compelled to register to the site and comment here even though I do not have MS.

     

    I do have CNS Lyme (a dirty word in the medical community) and I do have the results of so-called Sick Building disease (another dirty word). Both are out of favor because they are so costly, there is no cure, etc. etc....

    RHMLucky777

    Read More

    The article and comment thread was so good that I felt compelled to register to the site and comment here even though I do not have MS.

     

    I do have CNS Lyme (a dirty word in the medical community) and I do have the results of so-called Sick Building disease (another dirty word). Both are out of favor because they are so costly, there is no cure, etc. etc.

     

    Thank you ALL for your posts here. I am now no longer hesitant to re-initiate a decreasing, prednisone treatment regime short term to control a flare-up of mucus membrane swelling and pain (and head pain) and joint pain. I have some 5 mg and 1 mg leftovers from last spring.

  • Pooh Bear
    Aug. 15, 2011

    As with someone else in the thread, I do not yet have a 100% confirmed MS diagnosis, but they are working on it and believe it to be.  I have been dealing with this for about 11 years and it is getting significantly worse.

     

    I am in the 5th week of 6 weeks of Prednisone.  During weeks 2 & 3 I felt fantastic, like I could actually handle the...

    RHMLucky777

    Read More

    As with someone else in the thread, I do not yet have a 100% confirmed MS diagnosis, but they are working on it and believe it to be.  I have been dealing with this for about 11 years and it is getting significantly worse.

     

    I am in the 5th week of 6 weeks of Prednisone.  During weeks 2 & 3 I felt fantastic, like I could actually handle the whole day of work, deal with the kids and do some housework, all in one day.  My gait went back to normal for a few days, too.  However, I think I got too excited, had too long a day and ended up in bed for a day in the middle of week 3.  Now, the pain/numbness, gait, etc. are all coming back slowly.

     

    I just looked into your thread to see if anyone else experienced just a short-term fix or if most experienced at least a few weeks or months relief from symptoms.

  • gloria
    Jul. 15, 2011

    Did you know that sucralose (splenda) causes MS symptoms in some folks.

     

    It causes at least three different combinations of symptoms.

     

    Some feel Lupus symptoms.

    Some feel the dull fist in the lower left rib.

    Some feel MS symptoms.

     

    Search the internet and YouTube and you will read all about the horrible

    side effects people get from eating...

    RHMLucky777

    Read More

    Did you know that sucralose (splenda) causes MS symptoms in some folks.

     

    It causes at least three different combinations of symptoms.

     

    Some feel Lupus symptoms.

    Some feel the dull fist in the lower left rib.

    Some feel MS symptoms.

     

    Search the internet and YouTube and you will read all about the horrible

    side effects people get from eating the common poison Chlorine.

     

    There is a video on YouTube called Sucralose Chlorine: A comparison. In video 2 and 3 it lists all of the public's specific complaints about this artificial sweetener.

     

    BTW aspartame (equal, acesulfame potassium (K)  is also a bad nasty.

    It will give you seizures, brain tumors and lower your serotonoin giving you depression, rage, anxiety and suicidal tendencies!

     

    If you have to use non-sugars use Agave or Stevia. Stay away from the two above, and read your labels for your kids because they are both in all of their things, from vitamins to chewing gum to pedialyte to popcorn, etc... everything even non-diet. (lunchables! too)

     

    Be healthy!

    btw, if you found that you eat those poisons and have those symptoms, stay off of them and most symptoms will disappeare (some neurological ones may not, but Essential Oils can help you - www.youRno1.org)

     

    www.youngliving.org/gil

  • Anonymous
    kim curtis
    Jun. 29, 2011

    I developed Crohn's disease at about 5 weeks into my pregnacy.

    This was not common and after trying a number of medications.

    Predinsone was all that worked. By worked I mean made the Crohn's

    controllable some what. My story involves about 5 years struggle to survive so

    I will make it short.

    Bed rest at 5 weeks pregnant and stayed there for 6 months, until...

    RHMLucky777

    Read More

    I developed Crohn's disease at about 5 weeks into my pregnacy.

    This was not common and after trying a number of medications.

    Predinsone was all that worked. By worked I mean made the Crohn's

    controllable some what. My story involves about 5 years struggle to survive so

    I will make it short.

    Bed rest at 5 weeks pregnant and stayed there for 6 months, until my son was

    born. I lost 78 pounds and 4 inches of body fat. I looked like my skin hung off me.

    Had to build up my strength over the next two years before I was able to return to working. But with Crohns part time is all my body could handle at first.

    All while taken Predinsone everyday and some time at twice the suggested doses.

    But everytime I would get down to 60 or less the GI bleeding and pain came

    back full blown.

    Did this up and down with Predinsone, raisin my son, trying to work, sick all

    the time. My weight was different everyday. I would be a size 5 then the next day a size 7. Swollen from the side effects at that point was all I had.

     

    Now jumping to now 15 years later. I am in remission and 42 years old.

    I am finding out just what Predinsone abuse means. BAD Within the last 24 months. I have been diagnosed with Osteoporosis, gun disease, cateracts and major vision changes. All are from taking Predinsone for to long, extended bed rest. Which if I had not done at the time I would not be here today.

    But telling me at age 25 that Predinsone has side effects did not even prepare me enough.

     

    I am actually wanting to let people know if at all possible do not take Predinsone. Yes, for poison ivy, strep thoat or colds, dose packs are great.

    And dont have these side effects. But the pain, trouble, and fear I am dealing

    with now sucks. Being 42 and having a body that is approx. 63 (DXA results)

    is not even what I would have exspected.

     

    thanks for listening...kcurtis 

  • JackB
    Apr. 28, 2011

    I am 24 year old male and was diagnosed with MS 4 years ago. Typically when I have a bad exacerbation I do an infusion of solumederol @ 1g a day for 3-5 days. Then a taper to wean off for a week or two.  Recently, because my relapses are coming in 90 day intervals, I was directed to a specialist in Miami.  He had me try a Prednisone oral dose of 1250mg...

    RHMLucky777

    Read More

    I am 24 year old male and was diagnosed with MS 4 years ago. Typically when I have a bad exacerbation I do an infusion of solumederol @ 1g a day for 3-5 days. Then a taper to wean off for a week or two.  Recently, because my relapses are coming in 90 day intervals, I was directed to a specialist in Miami.  He had me try a Prednisone oral dose of 1250mg (1.25g) a day for 5 days then taper off.  Studies are showing relative effectiveness when compared to the infusion.  For me personally I handle the oral much better than the infusion. My side effects on the oral typically are night sweats, increased appetite, mood swing (around day 3-4), restlessness.

     

    I highly reccommend talking with your neurologist if you are being put on infusions to discuss the oral treatment of 1250mg/day for 5 days.  Huge benefits including starting/finishing treatment over the weekends and cost. Just to be blunt, my oral treatment only costs me $30 with my insurance as opposed to outpatient costs and time taken off for the infusion. 

     

    If you would like to know the treatments I have already tried they are Rebif and Copaxone. Neither helped keep me from relapses as according to their studies. I will be starting Gilenya soon.  

     

    I hope this helps encourage you! And don't forget to enjoy life!

     

  • chris
    Mar. 04, 2011

    I finished a course of steroids last week for optic neuritis only took half of the course because id heard some bad things about them i was on 4 pills for the first five days then reduce by one every four days i dident have any side effects that im aware of felt good i still feel good hope it lasts

  • Anonymous
    Prednisone Veteran
    Jan. 31, 2011

    I have been on prednisone off and on about every couple of months or so for the last 3 1/2 years.


    I have a history of pericarditis and pleural effussion (I was hospitalized on two different occasions a few years back and both had to be drained).  Since then, I get terrible inflammation pain back every couple of months (but no fluid) and prednisone is the...

    RHMLucky777

    Read More

    I have been on prednisone off and on about every couple of months or so for the last 3 1/2 years.


    I have a history of pericarditis and pleural effussion (I was hospitalized on two different occasions a few years back and both had to be drained).  Since then, I get terrible inflammation pain back every couple of months (but no fluid) and prednisone is the only thing that makes the pain go away.  No one can tell me what the cause was or is other than "it's some virus your body can't get rid of, but we don't know what the virus us."  Even the Mayo Clinic in Rochester.....

     

    With prednisone, I always feel better after or around the 2nd days dose.  But I am always full of energy, hungry, don't sleep well (wide awake at night), and I tend to get very warm (during the night and sometimes daytime as well).  I gain weight...in fact - I'm about 35 lbs overweight now.  But with this pain every few months, I feel like it's a viscious cycle that I can't overcome...I'll probably be on prednisone like this the rest of my life. :(

    • Anonymous
      Chronic Inflamm...
      Mar. 18, 2011

      To Prednisone Veteran:  Are you taking the Medrol Pak?  I have just been prescribed this dosage.  Am looking for a safe protocal to take for OA and Chronic Inflammation.  Anyone else have this problem?  Also, diagnosed with severe case of Parvo Virus years back and had to take Medrol Pak (helped the rash)......can such a virus continue...

      RHMLucky777

      Read More

      To Prednisone Veteran:  Are you taking the Medrol Pak?  I have just been prescribed this dosage.  Am looking for a safe protocal to take for OA and Chronic Inflammation.  Anyone else have this problem?  Also, diagnosed with severe case of Parvo Virus years back and had to take Medrol Pak (helped the rash)......can such a virus continue to damage your body long after the initial bout?

  • Carepal
    Dec. 06, 2010

    Thank you for your post. I just recieved a 4MG DOSEPK and I was afraid to take it for fear of weight and water gain.  For me, it's a short term fix while the doctors decide if I have MS or Lupus.  Either way, I wouldn't have taken it if it wasn't for your thoughtful post. 

  • van
    van
    Oct. 28, 2010

    so far i am taking it for a small rash on the skin and i had lost a little sleep, urinate more than normal, appetite stay the same, horney just develope about 2 days ago, a little restlessness, my mentruation is not coming yet, which is unsuall. the rash now look like there are a small line of red vein visiable on my skin. I still have ten days to go of the...

    RHMLucky777

    Read More

    so far i am taking it for a small rash on the skin and i had lost a little sleep, urinate more than normal, appetite stay the same, horney just develope about 2 days ago, a little restlessness, my mentruation is not coming yet, which is unsuall. the rash now look like there are a small line of red vein visiable on my skin. I still have ten days to go of the medicine. I have noticed a little specks of blood in my urine. I will see if it will continue in the morning.

  • Anonymous
    Floridian
    Sep. 03, 2010

    Prednisone should not be taken with Melatonin.

    • Anonymous
      Terri
      Sep. 07, 2010

      I am on my second week of a two week course of prednisone treatment for chiggers bites! It was horrible! Much less horrible than MS or some of the other chronic conditions I am reading, but I wanted to share my experience with the side effects. Sleeplessness UGH! Its bad... Weight gain, I had been actually on the road to losing weight and was really happy about...

      RHMLucky777

      Read More

      I am on my second week of a two week course of prednisone treatment for chiggers bites! It was horrible! Much less horrible than MS or some of the other chronic conditions I am reading, but I wanted to share my experience with the side effects. Sleeplessness UGH! Its bad... Weight gain, I had been actually on the road to losing weight and was really happy about it and now I am not only stuck, but have gone back up by 5 lbs. My face and body is bloated like all hell. The indigestion and I guess just general burning in my stomach and throat is yucky. I eat before I take the pill but it doesnt help. I drink milk to try to relieve the symptoms a little. But it is just kind of a constant sourness. I have been such a grump the last week, just real, I dont know, not depressed, not pissed, not sad, just grumpy I guess. Mood issues side effects. I cant wait to get off of these stupid pills. Now here is the worst part. I am also on Topomax, which is a migraine preventative medication. Now this has its own set of side effects. Tingling hands and feet and change of taste buds. But now with the prednisone the taste in my mouth is horrible and constant. I have a constant sickeningly sweet taste in my mouth. Everything tastes different. I cant drink sodas, beer, actually anything carbonated, coffee tastes terrible, solid foods seem to be ok, mostly it is beverages, but the constant sweet taste is killing me. Anyone else have this issue? Or could it be the comibination of the two meds?

    • Wendi
      Mar. 10, 2011

      I was taking prednisone eye drops. Had swelling and rash on face . I also had a very bad taste in my mouth. It tasted metallic like. I have been off the drops for 3 weeks and still have the taste the swelling and allergic reactions stopped about a week after stopping the drops.  Has any one else experienced the metal taste while and after taking prednisone...

      RHMLucky777

      Read More

      I was taking prednisone eye drops. Had swelling and rash on face . I also had a very bad taste in my mouth. It tasted metallic like. I have been off the drops for 3 weeks and still have the taste the swelling and allergic reactions stopped about a week after stopping the drops.  Has any one else experienced the metal taste while and after taking prednisone ??

    • Tami Strickland
      Nov. 17, 2010

      On final 3 days of a 17 day prednisone treatment. Started w/ 5 days at 500 mg/day. Other than the size of the tablet and the taste, I felt I was continuing to worsen, but I was trying to convince myself I was feeling better. I am only now noticing my walking is starting to improve, and the aches/pains are lessening.  The insomnia begain immediately. I...

      RHMLucky777

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      On final 3 days of a 17 day prednisone treatment. Started w/ 5 days at 500 mg/day. Other than the size of the tablet and the taste, I felt I was continuing to worsen, but I was trying to convince myself I was feeling better. I am only now noticing my walking is starting to improve, and the aches/pains are lessening.  The insomnia begain immediately. I had more energy from 2:30AM-5:30AM than I've seen in 30 years. I never  want to feel compelled to go from sleep to fully alert doing laundry or the bathroom. Up until today, I thought my only complaint was the insomnia.  I was on a call, and it was very clear to myself, that my attitude has gone through a horrendous change. I have now had 2-3 people contact me (work relations) in the last hour asking if I am ok.Up until now, I took the warning of change in personality lightly, but I can report that the effect is definitely real. My episodes are bad enough to warrant apologizing afterwards because I am so over the top in my behavior. Lord bless me and forgive me.  I know the benefits outweigh these effects.

    • Anonymous
      Jean
      Apr. 25, 2011

      Did you really mean 500mg of prednisone?!!  That a really big dose of prednisone.

    • Anonymous
      heathb
      May. 16, 2011

      I was wondering the same thing... I have never heard of someone taking 500 mg. That can't be right. I've been taking prednisone for the past 7 months and the highest dose I've been on is 40 mg and I haven't been able to get my condition under control. That must have been a typo!

    • Anonymous
      Ashley J
      May. 19, 2011

      I have just started prednisone. 10mg tablets... 3x's a day for the first 2 days then 2 a day for the next 3 days and then 1 a day for 2 days... I noticed fast heart rate... shakey hands (not too bad..) Yes, I feel the energy... I always had insomnia but I work 3rd and I am usually dead by 4 and it's now 6 and I'm fine... I'm suppose to start today  so...

      RHMLucky777

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      I have just started prednisone. 10mg tablets... 3x's a day for the first 2 days then 2 a day for the next 3 days and then 1 a day for 2 days... I noticed fast heart rate... shakey hands (not too bad..) Yes, I feel the energy... I always had insomnia but I work 3rd and I am usually dead by 4 and it's now 6 and I'm fine... I'm suppose to start today  so my mood change could be PMS but I have been a little emotional. I didn't notice it til I started taking the meds. It's hard to tell the water weight because I always have water gain around this time of the month.. I do have some hot flashes tho... I am taking this for an allergic reaction in my ears, throat, and lungs..

    • Anonymous
      ATLGALadee
      Aug. 22, 2011

      I notice we are taking this med for the same reason and were given similiar instructions. By any chance, did you experience nausea and diarrhea? Thats what Im experiencing now? (Im waiting 2 hear from my doc 2 see if he wants me to continue taking this?

    • Shannon
      Jun. 30, 2011

      I was just prescribed prednisone (starting it tomorrow). I am to take 12 pills of 50m...yes 50 each twice a day for 3 days. I have been warned it is an extremely high dose by both the Dr and pharmacist and I am very nervous about it. It is for an exacerbation in ms...my worst yet and my first time on this drug. I have refused drugs in the past and...

      RHMLucky777

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      I was just prescribed prednisone (starting it tomorrow). I am to take 12 pills of 50m...yes 50 each twice a day for 3 days. I have been warned it is an extremely high dose by both the Dr and pharmacist and I am very nervous about it. It is for an exacerbation in ms...my worst yet and my first time on this drug. I have refused drugs in the past and just dealt with my symtoms but this time they are so bad I am willing to try anything. I'll comment back in 3 days...wish me luck

    • Anonymous
      Bryan
      Nov. 12, 2013
      500 mg of prednisone is what I read!? I can only imagine how terrible that was. I have been on prednisone for over two years straight. The highest i was ever prescribed was 320 mg a day. I was diagnosed with ALL (acute lymphoblastic leukemia). The blood cancer. That was my beginning dose, the 320. I am now cancer free, but have major problems with graft vs....
      RHMLucky777
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      500 mg of prednisone is what I read!? I can only imagine how terrible that was. I have been on prednisone for over two years straight. The highest i was ever prescribed was 320 mg a day. I was diagnosed with ALL (acute lymphoblastic leukemia). The blood cancer. That was my beginning dose, the 320. I am now cancer free, but have major problems with graft vs. host disease. It's a long explanation, but apparently prednisone is the only thing that can cure it. Unfortunately it has given me osteopenia and osteoporosis all over my body according to my dexta scans and X-rays. I also noticed the metallic taste and insomnia. Wow, now I know what tweakers must feel like. The swelling is terrible all over my body and when I tried to get back in the gym because i use to bodybuild, I caused myself injury. All thanks to prednisone. Hopefully my taper will be over in 3 months. Lets not forget my mood swings, depression, and extreme sensitivity. I'm not a tough guy or anything, but I balled like a baby watching green mile! Dont get me wrong, its a sad flick, but I couldn't stop the tears! Lol