The doctors initially diagnosed me with Relapsing Remitting MS, but they had misinterpreted the rapid progression as a relapse.  After discussing it with two neurologists, they changed it to Primary Progressive.   I diagnosed myself with MS four years ago at the age of 51; a tingling in my fee would not go away.  After two weeks, I knew what I had.  My mother had MS the last forty years of her life, so I knew what it looked like.   I used to be physically active as a factory laborer, setting a company record in 2000 for lifting 80,000 pounds in a 12-hour shift.  Today I am bedridden; have been for a year.  I tried to attend an MS convention in Atlantic City two weeks ago, but the wheel chair overturned at the front door.  The EMT's got me back inside, upstairs, and back in bed.  I gave it my best shot.   Today I just write about astrophysics and astronomy, maybe 700 essays in the last couple of years.  By now, the collection of images that goes along with them is big.  I do not think about MS much, but after reading the posts above, I realize that I need to pay serious attention to diet.  injectable drugs do not have any effect except to consume $23,000 a year.  There are none tailored for Primary Progressive; I take them in hopes that they might keep me from getting worse later.  Considering how fast I have gone South with them, it is now reasonable to say they do not work.   Well, it is time to get back to writing.  Contact me if you feel like talking.   David Madison Pennsylvania, USA (610) 792-3189 Home proplyd@verizon.net