Kerry, I am Charlene and my husband Mike 46 was diagnoised Dec. 2008....he was in and out of the hospital for different viruses..etc for 4 years...his MRI shows he has about 10-15 leisons in the brain and a T2 in the corbus collesum....his spinal taps (3) comes back negative...which with PPMS they do... I'm right their with you girl....our husbands are very tired at the end of the day...BUT encourage your husband to stay active...Mike works in the yard...walks the dog...and believe it or not he plays tennis...now he may not play like he used to but he's playing.... read about his diet also...use the fish oil...a good multivamin...Mike doesn't take any mediciations...be aware that if he says he doesn't feel like doing something just say "thats fine we will do it another time"...also depression is a factor with PPMS...our neighbor works for the best neurologist in our area and she was able to get my husband in last year and he diagnoised him.....the doctor told my husband it takes about 1 year to see how the progression develops to honestly say that he has PPMS...but they are happening....I just pray for him everyday...just know that for men it is really hard for them to be sick...yes different than us women....your life will change...emotionally, sexually....just know that this can progress differently for each patient....I will be glad to talk to you anytime...just feel free to contact me...my home email is boonefam@charter.net. God Bless You, Charlene