Thanks for the reply.  If you dont mind me asking - is your MS quit severe?  Have you ever looked into options other than those recommended by the doctors at UBC ... from what I've hear UBC is one of the best facilities but at this point in my aunt's illness there isnt much they can do (so they say) I have done extensive research and have found a few doctors that are doing some experimental treatments such as a doctor at the John Hopkins Institution ... have you ever looked into options across the border?  Do you know if there is a world re-known MS Specialist .. I am trying to find a doctor that is very well known for treating progressive MS.