Hi Shirley.  I was diagnosed with PPMS February 2000.  After having a major illness bout in November 1999.  I could't walk without pain and my body had curved over with severe spasms.  My primary doctor gave me neuronton which I took for a year. It really helped.  I went on Avonex injections for a period of approx. 6 years. I no longer take the injections.  My progress was slow.  I fell broke my hipbone and afterwards progression increased.  I now use a walker.  I have heard a lot about LDN and was told that "it really works for people who are PPMS.  My MS is on the left side of my body.  Including arm, hand, leg and foot.  I have what they call lawm mower gait or foot drop.  I live in Southern California and would like to try the LDN.  Do you know of places in Southern California that would Prescribe this medication.  My doctor will not prescribe this for me.  Also, I will need a compounding pharmacy.   Thank you for any info you can provide. Stay positive.  Mary