Hi Donna! I was just surfing the net for any kind of new info on pri-prog ms and I came across your question.  My mother-n-law has pp ms and has been on just about every kind of med you can think of.  I have watched her for 15 yrs, trying to come up with something that works.  And this is what I have concluded.  First of all, doctors will put you on anything and everything.  Why is this?  In her case, I believe it is done to give some kind of hope...but what has happened is she is almost broke from paying out muchmuch $$$ on the different kinds of treatments (I have a prob with the partnering of doctors and pharmaceutical co.s).  But physically, nothing.  She was just told last week that they were taking her off Tysambri (thank God!) after having injections for over a year.  ONce again, no substantial claims that this med helps pp ms, but the doctor is pacifying her mental need for medication.  SO DANGEROUS!  How do we know the med is not working?  Her brother had the same type ms and never took any type of injectible drug and his rate of progression was the same.  Sooooo...in drawing conclusions, I and my husband (her son) have begged her to not waste her disability check on the needless round of drugs.  Her best bet was (and is) physical therapy (keep the muscles working), rest, and if one feels like they need some type of therapy, then try the natural way (ie bee stings, flaxseed oil, oxygen therapy-used often in UK).  As for the doctor's bedside manners, she has gone through the same.  I believe the prob is they just don't know what to do.... I WILL be praying for you and for those dealing with this disease.  God is walking with you. Trea