Oral prednisone is used in two ways to treat MS relapses. It can be used in very high doses, in a similar way that intravenous steroids are used, to reduce the duration and severity of a relapse. Oral prednisone can also be used after a round of intraveous steroids (Solumedrol) to taper down from the extraordinarily high doses of IV steroids.
Just like with intravenous steroids, oral steroids may take a few days to show effectiveness. But it really depends upon what you are taking the steroids for and how long you've had symptoms.
My first attack was optic neuritis and the inflammation caused my right eye to go completely gray. The neuroopthalmologist and I opted for oral Prednisone instead of Solumedrol. Even though I took very high-doses (1000mg) each day for a short time period, it still took almost two months before my vision was back to normal.
I think that steroids may work more quickly with minor symptoms, and with more severe symptoms, Solumedrol is more commonly used. The decision to use oral steroids rather than IV steroids is one to be made with your doctor.
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This is a really good question!
I have a post written about this very topic as I just recently took oral Prednisone for the very first time for a bad exacerbation of my MS symptoms.
First of all...let me give you some information from Health Central about Prednisone.
And secondly let me tell you about my personal experience with using this drug. Everybody is going to react differently to the drugs but it was my experience that by the third day...I was feeling significantly better. I was taking 60 mg for four days and then 40 mg for four days and then finally 20 mg for four days. I would say by day five I experienced no MS symptoms whatsoever. So it definitely worked for me! But I imagine that it all depends upon the dosage and what sort of symptoms you are experiencing.
I hope this helps and perhaps others can chime in with their knowledge and experience.
Thank you for your question!
I am a 52 year old female. I am currently on day one of a second set of prednisone tapers: today is day 1, 60 mg of a prednisone taper. Last time I took a prednisone taper (about 6 months ago) ALL muscle and joint pain was essentially gone-went away by about day 5 or so. Rashes I thought were excema or something were completely gone during the treatment. It was a wonder drug. I felt good...well except for the insomnia side effect.
Severe pain came back about a month after taper ended and has become nearly unbearable to move around. I am yet undiagnosed. Health problems have come and go for last 10 years or so about 18 months apart. Currently I have had join, muscular pain for most of last 2 years. During these flare ups or episodes I also get higher than normal blood sugar (not diabetic), liver, kidney lab values, bad whole body fluid retention, fatigue, shortness of breath too. All auto-immune tests have come back negative. I have 2 siblings with auto-immune (thyroid and skin), one first cousin with MS and 2 first cousins with systemic lupus. Prednisone taken as directed seems to be a wonder drug, I just wish I had a good medical treatment plan other than just treat the symptoms here and there as they come.
I went to the doctor last week because for about 1 1/2 days my feet and lower legs felt like I was wearing tight socks and loss of some feeling. She put me on oral prednisone and said to let her know if that does not work or symptoms get worse. They did. Now I have that feeling up to my hips and pins and needles in my feetand my joints are very stiff. I have been on the prednisone for 5 days now and I don't think it is getting better. But I know that if I call the doc she will want to put me on the solumedrol but we changed ins.so that is another $1500 deductible, after meeting $1000 in Feb. on old ins. I don't mind spending the money if it's the only way, but I just was hoping this would work and don't know how much longer to wait.
Thank you for the advise!
Hello I was diagnosed with ms in 2005 but on sunday July 31 I had a really bad attack so my dr prescribed prednisone (20 mg). Do anyone know when I will begin to see results of this drug working