Sunday, January 11, 2009 Buffy, Community Member, asks

Q: Re: my previous question - non-specific high t2 signal abnormality in frontal subcortical w.matter

Thank you lisa for replying to my question so quickly. 

My answers to your questions are yes - I had all the blood tests testing for other diseases and they were all fine.  I have seen a neurologist who did various tests like making me walk in a straight line, resistance tests and tapping my fingers etc.. I passed all the tests except for when standing with my eyes closed I fell slightly to the right and I had descreased feeling in my right side when he did the pin prick test. 

My mri scan of head and neck lasted 40 minutes and they didn't inject dye, the scan of my head showed non-specific high T2 signal abnormality in frontal subcortical white matter (what does this mean?) and the scan of my neck showed I have mid cervical c5/6 left paracentral spondylotic disc in the absence nerve root impingement or cord compression - could this be causing the numbness in my arm/leg? The neurologist also writes in his letter that he doesn't think my mri results is relevant to my neurological history i.e. I was referred because of right sided migraines and numbness in right side (see previous email). What does he mean by that?  I am awaiting an appointment to go back and see him but if you can enlighten me a bit more so I know what to expect then that would be much appreciated.

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Answers (1)
Lisa Emrich, Health Guide
1/11/09 11:44pm

Hi Buffy,


Keep in mind that I'm not a medical professional, just a patient with MS.  It's a good thing that the blood tests have come back fine.  Certainly your neurological exam sounds positive.


More on the radiologist report - "mid [did you mean MILD?] cervical c5/6 left paracentral spondylotic disc in the absence [of] nerve root impingement or cord compression"


Perhaps - mild cervical spondylosis (ie. degenerative osteoarthritis) at c5/6 level on the left side near the center without cord compression or nerve impingement.  Common over age 40 with most people not losing nerve function.


More on the radiologist report - "non-specific high T2 signal abnormality in frontal subcortical white matter"


Perhaps - White matter is one type of brain matter which includes myelin.  Frontal subcortical refers to a specific area of the brain which controls aspects of our executive functions, emotions, and impulse control. 


T2 refers to a particular type of imaging cycle which produces clearer pictures.  Non-specific high signal abnormality means that some non-specific spots showed up on the image.  However, as we age, it is normal to have some abnormalities show up in the brain.  Comes with aging.


I don't know what exactly your next appointments will focus upon, sorry.  You can only take it one step at a time.  Wish I could say more....

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By Buffy, Community Member— Last Modified: 12/01/12, First Published: 01/11/09