Hello   I have to tell you that whenever I see this type of question I cringe.  Why?  Because I have MS and I ain't ready to die nor do I wish to think about dieing.    But sometimes it is best to face your fears head on and find out what the truth is is you can find it.   First of all you can read my first attempt at answering this question posed earlier...here.   I am going to also give you a quote that I have heard given repeatedly in the literature:  "A small number of patients have malignant MS, which is marked by a rapid decline that leads to disability and possibly death. MS is rarely fatal, however, and most people with the disease have a normal life expectancy."  ( Ed Zimney MD, Health Talk Medical Reference.)   The literature that I have read seems to be in consensus that you do not die from Multiple Sclerosis.  What you can die from are some of the complications arising from having MS.   What are those complications?  Usually respiratory distress or pneumonia.  Here is a study detailing the causes of death for people who have MS.  This study states that:  "Median observed survival time was 38.0 years from symptom onset."   Now if you really want to get into the details of what the end of life might be like for someone who has MS here are some articles you can pursue.   This article is about a man who lived in a hospice who had MS and this is the story of his circumstances.   Here is a story about a woman who died from a rare form of Primary Progressive MS.   And here is a question posed to a doctor about a woman's mother who is in her later stages of Multiple Sclerosis and she pretty much asks what you are asking.  The doctor answering pretty much confirms what the literature says...that you don't die from MS but rather from complications arising from MS such as blood clots or infections.   When I was first diagnosed I wanted to know all of this too.  I wanted to see the worst case scenarios.  I feel a lot more confident knowing that most people live to near life expectancy despite having MS and many people who have MS are not severely disabled by this disease.    I would much rather focus on the knowledge that Multiple Sclerosis does not mean that life is over.  I will leave you with this inspirational young man's message re-affirming this very message.