I am currently having "Extreme Burning Itching under the skin" along with deep pain seemingly in the joint or bone. There is NO rash or hives, like I said it is under the skin in the tissue and its been going on for over a month now. Occurring in my Feet, toes, hands, fingers and sometimes knees. It is the worst in the late afternoon/evening it moves around. the area swells up and is Red when affected. I am concerned because My father had both MS and Rheumatoid Arthritis. I have recently started up running and ran 2 5K's last month the symptoms started 4 days after my last 5k. Can anyone help me?