Christopher,thank you so much for all the information. It is ironic to get this today. It  has been a huge decision . I have been on the gilenya for 3 months today and feel worst than I ever have. I hope you dont mind me rambling but this has been a really bad day. 6 months ago I went to 2 different doctors in the same week for two different reasons and found out it was all due to the MS. cognitive and vision. within a couple of months I was experiencing the cognitive,vision, spasticity, what I am being told is called the MS HUG, numbness in the left side and horrible bouts of fatigue. I have not had more than 4 days of relief from any symptoms except the optic neuritis. That is one thing that I know the Gilenya has helped. Since I have been on the gilenya I have also had to go on blood pressure meds because of increased blood pressure that I have never had before. At this point I feel that the gilenya is not working for me. On top of everything else my insurance co. called me yesterday and informed me that they will know longer pay for my meds. I was paying 2,000.00 month but now I will be paying 2,700 month because novartis will pay 900.00 needless to say that was also discouraging.Do you think that I am not giving the gilenya a fair chance?  I honestly don't know if I can continue to pay that amount when I don't feel that it is doing me any good. Have you ever heard anyone that the disease lay dormant for 47 years and then all of a sudden have all these symptoms at once? I am so confused.My dr. says it is rrms but I feel it has not remitted in 6 months. when he diagnosed me with rrms he had only seen me once and that was when he ordered all the test and then the day he confirmed the diagnoses. and at that time I only had the two symptoms . I know I am rambling but I just feel like a crazy person ,not knowing what to do next.thanks so much for listening and giving me all this information. It really helps. Dawn