Yes - I have MS and have had considerable pain in both legs going right down to my ankles and across the top of my feet. It is like being right in front of a burning fire. I have started taking Gabapentin tablets daily, and have been given doses by my doctor of 3 tablets a day. I went to see my doctor because I felt that although the tablets were a great help in reducing the pain, they also interfered with my thinking, but just as important they also reduced considerably my ability to control the movement of both my arms and my legs. I am aware that this could possibly be my worsening MS, BUT having completely eliminated any use of Gabapentin before - it had helped my memory and thinking processes BUT increased the pain.   My doctor told me to persevere for a little more time until my body had got used to the drug, which I have now done, and the pain has definitely reduced in my upper legs though it still remains in my feet and ankles. So it would seem that the nerves flying down are not now attacking my upper legs. HOWEVER I know well that it is having an effect on my thought processes (which are still positive but can be very muddled and mixed with some frustration).   I have decided to take the full dose very soon, and will continue to research the effects it is having on my brain function, which if it continues to have effects I will eliminate any further taking of tablets and will find other possible sources of help whilst knowing that the pain will continue to effect me (right down my legs) which I probably will put up with, though take standard pain reducing tablets when needed.