7 Tips to Reduce the Pain of InjectionsFor subcutaneous (under the skin) self-injections, these tips should help eliminate some pain and lessen site reactions.
Room temperature medication
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Drugs which must be kept in the refrigerator for storage are often much less painful upon injection when at room temperature. Remove one syringe from the refrigerator and, while still in the wrapper, hold it in your armpit to bring it to body temperature.