SPASTICITY is one of the most common symptoms of multiple sclerosis (MS) that is seen in up to 75% of patients. It is a complex, poorly understood symptom that is often associated with muscle weakness. Often in MS, the lower limbs are more affected by spasticity than the arms. MS-related spasticity is usually the result of increased co-contraction of muscles during movement. Increased stiffness, or tone, can lead to decreased range of motion of major joints and result in shortening of...

