As with other autoimmune disorders, the exact cause of MS is unknown. A combination of environmental and genetic factors likely plays a role.
Multiple sclerosis is not hereditary, but genetic factors appear to play a role in making some people susceptible to the disease process leading to the condition. The most significant genetic link to MS has been identified in the major histocompatability complex (MHC), a cluster of genes on chromosome 6 that are essential for immune...
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Source: HealthCentral Encyclopedia
Article updated and reviewed by Associate Professor of Medicine / Neurology, Cooper University Hospital & Robert Wood Johnson Medical School on... Read more »