Researchers Develop Quick Way to Create Human Antibodies

That's a far cry from the one to two years typically required to make a single monoclonal cell line, Wilson noted.

Said Fauci: "The advance here is that now when you vaccinate someone, you can have literally within a week these very important antibody-secreting cells that can serve as the source for developing monoclonal antibodies. [ASCs] come earlier, they are in abundance, and have high-affinity antibodies. So that's a pretty important advance in cases where you need monoclonal antibodies for a pathogenic antigen."

In the event of an emerging flu pandemic, for instance, this approach could lead to faster production of human monoclonals to both diagnose and protect against the disease, he said.

More information

To learn more about therapeutic monoclonal antibodies, visit the American Cancer Society.

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