Leptin levels increase a great deal with every pound of weight that is gained, and obese people have a greater number of fat cells that produce leptin. When leptin reaches extreme levels, obese people become resistant to the signals that are being sent and become more vulnerable to leptin-induced blood clotting.
The association between obesity and blood clots is well known but the cause has remained a mystery. High levels of leptin caused by obesity could explain why.
References:
MedicineNet.com - http://www.medicinenet.com/blood_clots/article.htm - accessed 8/15/
UPI.com - http://www.upi.com/Health_News/2009/10/28/Obesity-increases-blood-clot-risk/UPI-46261256750471/ - accessed 8/15/12
Science Daily - http://www.webmd.com/dvt/news/20110428/being-tall-obese-may-boost-risk-of-blood-clots - accessed 8/15/12
WebMD - http://www.webmd.com/dvt/news/20110428/being-tall-obese-may-boost-risk-of-blood-clots - accessed 8/15/12
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My Story...
You can read about my decision to have weight loss surgery back in 2003, and since that time my journey from processed food junkie to healthy living so as to maintain a lifetime of obesity disease management. My wish is to help you on your own journey of lifetime obesity disease management. Whether you are planning or have had bariatric surgery, or you want to lose weight through non-surgical means, my shareposts along the way will help you to navigate your journey successfully.

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