Leptin levels increase a great deal with every pound of weight that is gained, and obese people have a greater number of fat cells that produce leptin. When leptin reaches extreme levels, obese people become resistant to the signals that are being sent and become more vulnerable to leptin-induced blood clotting.
The association between obesity and blood clots is well known but the cause has remained a mystery. High levels of leptin caused by obesity could explain why.
MedicineNet.com - http://www.medicinenet.com/blood_clots/article.htm - accessed 8/15/
UPI.com - http://www.upi.com/Health_News/2009/10/28/Obesity-increases-blood-clot-risk/UPI-46261256750471/ - accessed 8/15/12
Science Daily - http://www.webmd.com/dvt/news/20110428/being-tall-obese-may-boost-risk-of-blood-clots - accessed 8/15/12
WebMD - http://www.webmd.com/dvt/news/20110428/being-tall-obese-may-boost-risk-of-blood-clots - accessed 8/15/12
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