400 mg of Celebrex is a high dose. I am prescribed 400 mg of Celebrex, too, but for RA. I have asthma, also, so I take 10 mg of Zyrtec every day. I also take Celebrex, and various other medications. I am not a doctor. If you are concerned, you could call your pharmacist. None of my doctors have ever cautioned me not to take my antihistamine when I take my Celebrex.
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