Sunday, October 12, 2008 Nancy, Community Member, asks

Q: Does Lyrica help relieve arthritis pain?

My doctor prescribed Lyrica 75 mg/3 times a day for my osteoarthritis in my back (of course, it's also in my knees, hips, hands, elbows/...).  I was willing to try anything.  My back hurt so much I was turning into a grouch--I couldn't stand the pain! 


Is Lyrica used for arthritis?  How effective is it usually?

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Answers (4)
Casey McNulty, Health Guide
10/27/08 11:36am

Hi Nancy,


Thank you for your question. As you may known, osteoarthritis is a condition that affects your joints and your bones. Lyrica is not approved by the FDA to treat osteoarthritis. Lyrica is approved to treat nerve pain (called neuropathy), not bone pain. If you find that the Lyrica is helping improve your condition and your quality of life, then by all means you can continue taking it. However, if you find that you're not doing any better with the Lyrica after a few weeks, you could ask your doctor why he chose to put you on this medication since it's not approved for treatment of osteoarthritis, and ask to try something else.


Best of luck,


Kathleen, Community Member
2/28/12 6:32pm

I was diagnosed with osteoarthritis in my spine, hips, back, ribs, wrists and ankles.  My Rhuematologist put me on 75mg at bedtime.  I take 400mg of motrin at 3:00pm after my walk and take 650 tylenol muscle pain med at 8:00 for sore muscles.  I've only taken it one day.  They thought I had PMR at first and put me on 50mg of prednisone which I am weaning off right now.  It breaks down the bone even more the prednisone so no wonder after being on it for a month I got much worse.  It is for nerve pain and with arthritis you get alot of nerve pain when it is in the spine, or any joint for that matter.  I know they use this for MS too which is all about nerves.  Arthritis in the joints causes all the surrounding tissues and nerves to swell and be sore. 

Ceferino Perez, Community Member
8/ 5/10 6:41pm

Does Lyrica help relieve arthritis pain?

Kathleen, Community Member
2/28/12 6:33pm

IF you have swelling in your joints, yes it does.  Arthritis in the spine forsure.

MissDizzy, Community Member
10/21/10 3:02pm

Actually, my rheumatologist prescribed Lyrica for my spinal osteoarthritis.  She only prescribed it today, so I don't know yet if it will work.  I've heard of others being prescribed Lyrica for osteoarthritis as well.  It's an "off-label" use that's quite common.



Lu, Community Member
11/13/10 10:53am

I have been on Lyrica to treat my fibromyalgia.  It has worked very well on that so far, however, my osteoarthitis has gotten much worse.  I was searching for info to find out whether Lyrica might make those symptoms worse. 

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By Nancy, Community Member— Last Modified: 06/21/14, First Published: 10/12/08