Researchers at the Fisher Center for Alzheimer’s Disease Research at The Rockefeller University have published the results of their recent study, which showed that non-steroidal anti-inflammatory drugs (NSAIDs) reduced the effectiveness of selective serotonin reuptake inhibitor (SSRI) antidepressants.
NSAIDs include over-the-counter medications like ibuprofen, aspirin and naproxen as well as prescriptions drugs such as Celebrex, Daypro, diclofenac, etodolac, ketoprofen, meloxicam, Mobic, Naprosyn, Relafen, Toradol, Voltaren, etc.
You may be wondering what this study has to do with chronic pain. Antidepressants are sometimes prescribed as a treatment for chronic pain because they help increase serotonin, which is important for pain modulation. If NSAIDs prevent antidepressants from being effective for depression, they may also interfere with the ability of antidepressants to reduce pain. Study Design and Results Scientists first tested their theory on mice...
Generic Name: HYDROCODONE/IBUPROFEN - ORAL Pronounced: (HYE-droe-KOE-done/EYE-bue-proe-fen) Hydrocodone-Ibuprofen Oral Interactions
Drug interactions may change how your medications work or
increase your risk for serious side effects. This document does not contain all
possible drug interactions. Keep a list of all the products you use (including
prescription/nonprescription drugs and herbal products) and share it with your
doctor and pharmacist. Do not start, stop, or change the dosage of any
medicines without your doctor's approval.
Some products that may interact with this drug
aspirin or other NSAIDs (such as ketorolac,
anti-platelet drugs (such as cilostazol,
bisphosphonates taken by mouth (such as
"blood thinners" (such as enoxaparin, heparin,
corticosteroids (such as prednisone)
MAO inhibitors (isocarboxazid, linezolid, methylene blue,
Headache - mixed tension migraine
Certain things may cause your headaches. For example, some people get headaches after drinking alcohol or eating certain foods. These are called triggers. You should identify your specific triggers and avoid them as much as possible.
A headache diary can help you identify your headache triggers. When you get a headache, write down the day and time the pain began. The diary should include notes about what you ate and drank in the last 24 hours, how much you slept and when, and what was going on in your life immediately before the pain started. For example, were you under any unusual stress? Also include information about how long the headache lasted, and what made it stop.
Hot or cold showers or baths may relieve a headache for some people. It is important to follow a healthy lifestyle, get plenty of sleep, and to avoid stress as much as possible.
Over-the-counter medicines such as ibuprofen a...
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