To my knowledge, ibuprofen and Lyrica do not interact in a negative way. However, if you are taking aspirin to prevent a heart attack or strokes, the ibuprofen can block the protective mechanism of aspirin. Thus, aspirin and ibuprofen should not be taken together if your taking aspirin for that reason.
Dr. Christina Lasich, MD
We hope you find this general health information helpful. Please note however, that this Q&A is meant to support not replace the professional medical advice you receive from your doctor. No information in the Answers above is intended to diagnose or treat any condition. The views expressed in the Answers above belong to the individuals who posted them and do not necessarily reflect the views of Remedy Health Media. Remedy Health Media does not review or edit content posted by our community members, but reserves the right to remove any material it deems inappropriate.