Yes, cortisone. Cortisone is a steroid, which has significant anti-inflammatory properties. The relief can last for a few months, but doctors may limit the number of injections they will give because of the possible risk of cartilage damage with too many injections.   There's also Hyaluronan (also called hyaluronic acid), a substance in normal joint fluid that lubricates the joint, much like oil lubricates the parts of a car's engine. hyaluronic injections. Click here to read a post about hyaluronic injections for the knee.   You should talk to your doctor about these treatments and discuss what might work best for you. It may or may not be an injection.