I get Synvisc shots in my knees. They last six months to a year and help me a lot. I know others that don't get much relief from them, but we are all individuals. My doctor recommended these over the cortisone shots for my particular situation. I need total knee replacement in both knees. It depends on what is wrong w/your knee(s), I guess. It has been my experience that neither shot will "cure" most things, but I am not a doctor. Hope this helps! V
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