The FDA recently approved two new generic versions of Boehringer Ingelheim Pharmaceuticals Inc.'s popular anti-arthritis medication, Mobic. This medication, which treats the symptoms of both osteo- and rheumatoid arthritis, had sales of over a billion dollars in the United States during the last fiscal year. The two generic alternatives, known by the generic name Meloxicam, are produced by the Israeli company Teva Pharmaceutical Industries Ltd and Par Pharmaceuticals Co, Inc, and are available in doses of 7.5 and 15 mg. Find out more about Meloxicam here.
Researchers at the Fisher Center for Alzheimer’s Disease Research at The Rockefeller University have published the results of their recent study, which showed that non-steroidal anti-inflammatory drugs (NSAIDs) reduced the effectiveness of selective serotonin reuptake inhibitor (SSRI) antidepressants.
NSAIDs include over-the-counter medications like ibuprofen, aspirin and naproxen as well as prescriptions drugs such as Celebrex, Daypro, diclofenac, etodolac, ketoprofen, meloxicam, Mobic, Naprosyn, Relafen, Toradol, Voltaren, etc.
You may be wondering what this study has to do with chronic pain. Antidepressants are sometimes prescribed as a treatment for chronic pain because they help increase serotonin, which is important for pain modulation. If NSAIDs prevent antidepressants from being effective for depression, they may also interfere with the ability of antidepressants to reduce pain. Study Design and Results Scientists first tested their theory on mice...
Although triptans are a marked improvement over previous treatment options, many Migraineurs have not been fully satisfied with their results. Some do not achieve full relief from triptans, and the recurrence of Migraines within 24 hours of the first dose has been common. With the patents on sumatriptan nearing their expiration, both generics of the current forms – injections, tablets, and nasal spray – and other medications containing sumatriptan are now in development and testing. The results involving Trexima, one such medication that is a combination of sumatriptan and naproxen, have now been published. Read Study Finds Sumatriptan-Naproxen Combination More Effective against Migraine Attacks .
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