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Friday, October, 23, 2009

Ankylosing Spondylitis Diagnosis

Health Encyclopedia: Hla B27 Antigen

Alternative Names

Human leukocyte antigen B27


Normal Values

HLA-B27 is found in 5 - 7% of Caucasian people without autoimmune disease.


What abnormal results mean

A positive test indicates a greater-than-average risk for developing:

  • Ankylosing spondylitis
  • Reiter's syndrome
  • Sacroiliitis (inflammation of the sacroiliac joint)

In the presence of suggestive clinical findings, a positive HLA-B27 test may confirm the diagnosis.


Read more »

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Histocompatibility antigens
...common in certain autoimmune diseases. For example, HLA-B27 antigen is found in 80-90% of people with ankylosing spondylitis and Reiter's syndrome, and can aid in the diagnosis of these diseases.... Read more »
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Diseases that fall under spondyloarthritis umbrella are ankylosing spondylitis, reactive arthritis (known previously as Reiter's syndrome) psoriatic arthritis and psoriatic spondylitis, and the... Read more »
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...swelling, deep-vein blood clots, or both may occur. Piriformis syndrome is sometimes difficult to diagnose.Ankylosing SpondylitisAnkylosing spondylitis is a chronic inflammation of the spine that... Read more »
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