Degenerative Joint Diseases Affects What Body System

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Article updated and reviewed by Stephen Burnett, MD, FRCS(C), Assistant Professor, Department of Orthopaedic Surgery, Washington University School of Medicine on July 11, 2005.

A degeneration or ‘wear and tear’ of articular (joint surface) cartilage usually accompanied by an overgrowth of bone (osteophytes), narrowing of the joint space, sclerosis or hardening of bone at the joint surface, and deformity in joints. OA is not usually associated with inflammation, although swelling of the joint...

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